TABLE II

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Embryonic genes that are homozygous lethal found in the catalogue of preimplantation genes

UniGene #    Gene abbreviation and description    Gene abundances normalized for a library of 70,000 ESTs

2573    Ahcy: s-Adenosylhomocysteine hydrolase    6

37210    Ap1g1: adaptor protein complex AP-1, gamma 1 subunit (g-adaptin)    1

4189    Ccna2: cyclin A2    12

19133    Aplp2: amyloid beta (A4) precursor-like protein 2    6

21771    Cul1: cullin 1    40

3833    Rangap1: RAN GTPase activating protein 1    4

22722    Raly: hnRNP-associated with lethal yellow    6

2025    Smn: survival motor neuron    6

1886    Tebfip-pending: Tcra enhancer-binding factor interacting protein 1    5

231    Rad51: Rad51 homolog (S. cerevisiae)    1

33783    Gata6: GATA-binding protein 6    5

17031    Pou5f1: domain, class 5, transcription factor 1    12

1538    Btf3: basic transcription factor 3    32

26212    no gene symbol: ESTs, highly similar to SRB7 (H. sapiens)    5

27835    Bpag1-n: dystonin    2

35605    Cdh1: cadherin 1    15

1249    Lamc1: laminin, gamma 1    3

16340    Fgfr2: fibroblast growth factor receptor 2    4

6888    Plcb3: phospholipase C, beta 3    1

21482    no gene symbol: chloride ion current inducer protein (ICln)    12